View source for Guadalupe County, Texas

===2020 census===

As of the [[2020 United States census|2020 census]], the county had a population of 172,706. The median age was 37.7 years. 25.8% of residents were under the age of 18 and 14.7% of residents were 65 years of age or older. For every 100 females there were 96.4 males, and for every 100 females age 18 and over there were 93.5 males age 18 and over.<ref name="Census2020DP">{{cite web|title=2020 Decennial Census Demographic Profile (DP1)|url=https://api.census.gov/data/2020/dec/dp?get=NAME,DP1_0021P,DP1_0024P,DP1_0025C,DP1_0049C,DP1_0045C,DP1_0069C,DP1_0073C,DP1_0125P,DP1_0126P,DP1_0129P,DP1_0133P,DP1_0137P,DP1_0138P,DP1_0139P,DP1_0141P,DP1_0142P,DP1_0143P,DP1_0145P,DP1_0146P,DP1_0147C,DP1_0148C,DP1_0149C,DP1_0156C,DP1_0157C,DP1_0158C,DP1_0159P,DP1_0160P&for=county%3A187&in=state%3A48|website=United States Census Bureau|year=2021|access-date=January 9, 2026|df=mdy}}</ref><ref name="Census2020PL">{{cite web|title=2020 Decennial Census Redistricting Data (Public Law 94-171)|url=https://api.census.gov/data/2020/dec/pl?get=NAME,P1_001N,P1_003N,P1_004N,P1_005N,P1_006N,P1_007N,P1_008N,P1_009N,P2_001N,P2_002N,H1_001N,H1_002N&for=county%3A187&in=state%3A48|website=United States Census Bureau|year=2021|access-date=January 9, 2026|df=mdy}}</ref>

The racial makeup of the county was 59.7% [[White Americans|White]], 7.4% [[African Americans|Black or African American]], 0.8% [[Native Americans in the United States|American Indian and Alaska Native]], 1.9% [[Asian Americans|Asian]], 0.2% [[Native Hawaiians|Native Hawaiian]] and [[Pacific Islander]], 10.5% from some other race, and 19.4% from [[Multiracial Americans|two or more races]]. [[Hispanic and Latino Americans|Hispanic or Latino]] residents of any race comprised 37.8% of the population.<ref name="Census2020PL"/>

75.2% of residents lived in urban areas, while 24.8% lived in rural areas.<ref name="Census2020DHC">{{cite web|title=2020 Decennial Census Demographic and Housing Characteristics (DHC)|url=https://api.census.gov/data/2020/dec/dhc?get=NAME,P2_002N,P2_003N&for=county%3A187&in=state%3A48|website=United States Census Bureau|year=2023|access-date=January 9, 2026|df=mdy}}</ref>

There were 59,975 households in the county, of which 38.4% had children under the age of 18 living in them. Of all households, 57.4% were married-couple households, 14.7% were households with a male householder and no spouse or partner present, and 22.0% were households with a female householder and no spouse or partner present. About 19.8% of all households were made up of individuals and 8.5% had someone living alone who was 65 years of age or older.<ref name="Census2020DP"/>

There were 64,482 housing units, of which 7.0% were vacant. Among occupied housing units, 76.8% were owner-occupied and 23.2% were renter-occupied. The homeowner vacancy rate was 1.5% and the rental vacancy rate was 6.5%.<ref name="Census2020DP"/>