View source for Lycopene

===Adverse effects===
[[File:Lycopene in DCM.jpg|thumb|right|100px|Test tube containing a dichloromethane solution of lycopene]]

Lycopene is non-toxic and commonly found in the diet, mainly from tomato products.<ref name=lpi/>  There are cases of intolerance or allergic reaction to dietary lycopene, which may cause [[diarrhea]], [[nausea]], stomach pain or cramps, gas, and loss of appetite.<ref name="mayo">{{cite web
| title = Lycopene
| url = http://www.mayoclinic.org/drugs-supplements/lycopene/background/hrb-20059666
| publisher = Mayo Clinic
| date = 2017
| access-date = 29 May 2017
| archive-date = 23 September 2017
| archive-url = https://web.archive.org/web/20170923043049/http://www.mayoclinic.org/drugs-supplements/lycopene/background/HRB-20059666
}}</ref> Lycopene may increase the risk of bleeding when taken with [[anticoagulant]] drugs.<ref name=mayo/> Because lycopene may cause low blood pressure, interactions with drugs that affect blood pressure may occur. Lycopene may affect the [[immune system]], the [[nervous system]], sensitivity to sunlight, or drugs used for stomach ailments.<ref name=mayo/>

[[Lycopenemia]] is an orange discoloration of the skin that is observed with high intakes of lycopene.<ref name="pmid16046742">{{cite journal | vauthors = Trumbo PR | title = Are there adverse effects of lycopene exposure? | journal = The Journal of Nutrition | volume = 135 | issue = 8 | pages = 2060S–1S | year = 2005 | pmid = 16046742 | doi = 10.1093/jn/135.8.2060s| quote = <small>Lycopenemia, characterized by an orange discoloration of the skin, has been observed with high intakes of lycopene-containing foods. One case study reported the incidence of lycopenemia in a 61-y-old woman who had consumed ~2 L of tomato juice daily for several years (10). Although there was evidence of lycopene and fatty deposits in the liver, there was an absence of measurable hepatic dysfunction. After 3 wk of consuming a diet free of tomato juice, the orange discoloration faded.</small>| doi-access = free }}</ref> The discoloration is expected to fade after discontinuing excessive lycopene intake.<ref name="pmid16046742"/>