File:Peptide Synthesis.svg
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Original file (SVG file, nominally 692 × 310 pixels, file size: 95 KB)
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Summary
| DescriptionPeptide Synthesis.svg |
English: Solid-phase peptide synthesis |
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| Date | |||
| Source | Own work | ||
| Author | Dan Cojocari ✉·✍· | ||
| Permission (Reusing this file) |
I, the copyright holder of this work, hereby publish it under the following licenses: This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.
You may select the license of your choice. |
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| Other versions | File:Peptide Synthesis.png |
| Annotations InfoField | This image is annotated: View the annotations at Commons |
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Rink Linker that connects the solid resin to the peptide being built
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Solid resin for peptide synthesis
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The first amino acid (side group R1) conjugated to an Fmoc group that protects the amino end.
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Acid catalyzed (Trifluoroacetic acid) decoupling of the finished peptide and the linker. The linker ends up with and -OH group, instead of the initial -NH2.
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Basic conditions required in order to keep -NH2 ,not -NH3+
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Mechanism of acid-catalyzed uncoupling.
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29 November 2009
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 07:36, 12 August 2014 | No thumbnail | 692 × 310 (95 KB) | commonswiki>DMacks | rm in-image credit text |